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Post by Admin on Dec 22, 2023 18:27:33 GMT
A research team from RIKEN and other institutions announced on the 23rd that even after being infected with the new coronavirus, the heart may be continuously infected with the virus, increasing the risk of heart failure even if no noticeable heart disease develops. The results were announced. He points out that the number of patients with heart failure may increase rapidly in the near future, and calls for countermeasures.
Infection with the new coronavirus occurs when the protrusion-like "spike protein" on the surface of the virus binds to the receptor "ACE2" on the surface of human cells. According to the team, the heart is more likely to express ACE2 than other organs. Additionally, it has been reported that some people infected with the new coronavirus experience a decline in heart function, but the detailed mechanism is not known.
The research team first created heart tissue using induced pluripotent stem cells (iPS cells). When this animal was infected with a large amount of virus, its heart function decreased and did not recover. On the other hand, when patients were infected with a small amount of the virus, a certain level of heart function was maintained, but the infection continued even after four weeks. It is possible that some patients may not develop heart failure even if the infection persists.
Furthermore, when heart tissue was subjected to hypoxia to reduce cardiac function, uninfected cells recovered after a certain period of time, but cells that remained infected with a small amount of virus did not. Persistent infection appears to have weakened the patient's recovery function.
Hidetoshi Masumoto, a senior researcher (regenerative medicine) at RIKEN, said, ``There is a possibility that the heart may become persistently infected in some people infected with the new coronavirus.We are developing testing systems in preparation for a ``heart failure pandemic,'' when the number of heart failure patients will rapidly increase. "We need to establish treatments and treatment methods." The research results were published in the American scientific journal ``I-Science.''
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Post by Admin on Feb 21, 2024 21:59:48 GMT
The total number of confirmed cases of vaccine damage over the past 45 years in Japan is 3,522. Of these, 151 were certified as dead.
On the other hand, according to the latest data released by the Ministry of Health, Labor and Welfare (as of January 26), 10,135 applications for coronavirus vaccination have been received. Of these, 1,158 cases were related to death. Of these, 6,088 cases were certified, and 453 cases were certified as deaths. This shows that it stands out compared to all conventional vaccines.
The doctors said, ``With the goal of delivering results to patients and their families, we will develop a test method for post-vaccination syndrome that no one can deny, clearly provide information on side effects, and dissect the mechanism at the molecular level.'' I was enthusiastic. In the future, the company plans to establish a consultation desk in cooperation with local governments, medical associations, and other organizations.
Major media outlets were also reporting on the day of the press conference, but they have not reported on it yet.
The official name of the side effect is "post-vaccination syndrome." The press conference, papers, materials, etc. are available on the official website of the Vaccine Problem Study Group.
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Post by Admin on Feb 24, 2024 13:10:07 GMT
"I have almost never seen a case where a young person becomes seriously ill and is hospitalized. That is very different from the summer 2021 outbreak. Back then, there were cases where people in their 40s and 50s who had not been vaccinated became seriously ill and died. These days, there are many cases in which even elderly people are admitted to the hospital for preventive reasons, such as when they have no family members to care for them or when they have an underlying disease.''
With the transition to Category 5 of the new coronavirus, there are no legal rules of conduct for infected persons, with the exception of the School Health and Safety Act, which requires such measures as suspension of attendance for five days from the onset of symptoms. Even during the 10th wave, there are people coughing and sneezing without masks on the train.
Mr. Kiuchi says, ``It is important not to leave crisis management to others.'' He says there will be no problems as long as individuals can make decisions and change their behavior on a case-by-case basis, such as ``I'm wearing a mask because the coronavirus is spreading,'' or ``I'm not feeling well, so I won't go outside.''
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Post by Admin on Mar 17, 2024 10:42:07 GMT
Indonesia’s marked decline in marriage rates reflects stark shifts in socio-economic conditions, societal norms and demographic trends, analysts say, all of which have sparked concern among officials about the impact on the country’s fertility rate and economic future.
In its annual data release, published late last month, Indonesia’s Central Bureau of Statistics (BPS) highlighted an overall drop in the number of people getting married over the last six years, with the sharpest downturn occurring in 2020 during the Covid-19 pandemic.
In 2018, the BPS recorded 2,016,171 marriages in Indonesia but in 2020 the number nosedived to 1,792,548. Last year, it only registered 1,577,255.
Ironically enough, however, the recent shift in attitudes towards marriage and children partly stems from previous government policies, according to Ariane.
In the 1970s, Indonesian authorities rolled out a massive keluarga berencana (family planning) campaign to encourage couples to stop at two children, and laud the ideal marriage age as 25 for men and 20 for women.
“This ideational shift is still having its impact today as various studies have indicated that most Indonesians still subscribe to the Suharto-era ideals of having a small family,” Ariane said.
She further noted that delayed marriage would affect Indonesia’s overall fertility rate, saying the experience of other nations had shown reversing declining birth rates through policy interventions to be “elusive” at best.
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Post by Admin on Mar 20, 2024 3:04:43 GMT
"From the very early days of the pandemic, brain fog emerged as a significant health condition that many experience after COVID-19.
Brain fog is a colloquial term that describes a state of mental sluggishness or lack of clarity and haziness that makes it difficult to concentrate, remember things and think clearly.
Fast-forward four years and there is now abundant evidence that being infected with SARS-CoV-2 – the virus that causes COVID-19 – can affect brain health in many ways.
In addition to brain fog, COVID-19 can lead to an array of problems, including headaches, seizure disorders, strokes, sleep problems, and tingling and paralysis of the nerves, as well as several mental health disorders.
A large and growing body of evidence amassed throughout the pandemic details the many ways that COVID-19 leaves an indelible mark on the brain. But the specific pathways by which the virus does so are still being elucidated, and curative treatments are nonexistent. [...] Now, two new studies published in the New England Journal of Medicine shed further light on the profound toll of COVID-19 on cognitive health.
"Here are some of the most important studies to date documenting how COVID-19 affects brain health: Large epidemiological analyses showed that people who had COVID-19 were at an increased risk of cognitive deficits, such as memory problems. Imaging studies done in people before and after their COVID-19 infections show shrinkage of brain volume and altered brain structure after infection. A study of people with mild to moderate COVID-19 showed significant prolonged inflammation of the brain and changes that are commensurate with seven years of brain aging. Severe COVID-19 that requires hospitalization or intensive care may result in cognitive deficits and other brain damage that are equivalent to 20 years of aging. Autopsy studies of people who had severe COVID-19 but died months later from other causes showed that the virus was still present in brain tissue. This provides evidence that contrary to its name, SARS-CoV-2 is not only a respiratory virus, but it can also enter the brain in some individuals." [...] Drops in IQ
"Most recently, a new study published in the New England Journal of Medicine assessed cognitive abilities such as memory, planning and spatial reasoning in nearly 113,000 people who had previously had COVID-19. The researchers found that those who had been infected had significant deficits in memory and executive task performance.
This decline was evident among those infected in the early phase of the pandemic and those infected when the delta and omicron variants were dominant. These findings show that the risk of cognitive decline did not abate as the pandemic virus evolved from the ancestral strain to omicron.
In the same study, those who had mild and resolved COVID-19 showed cognitive decline equivalent to a three-point loss of IQ. In comparison, those with unresolved persistent symptoms, such as people with persistent shortness of breath or fatigue, had a six-point loss in IQ. Those who had been admitted to the intensive care unit for COVID-19 had a nine-point loss in IQ. Reinfection with the virus contributed an additional two-point loss in IQ, as compared with no reinfection. [...] To put the finding of the New England Journal of Medicine study into perspective, I estimate that a three-point downward shift in IQ would increase the number of U.S. adults with an IQ less than 70 from 4.7 million to 7.5 million – an increase of 2.8 million adults with a level of cognitive impairment that requires significant societal support."
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