Post by Admin on Jul 16, 2024 11:36:48 GMT
Allelic comparison between Tunisians and other populations
The frequencies of HLA alleles in Southern Tunisians were compared with those of other Arab-speaking, Mediterranean and sub-Saharan populations by high-resolution HLA-DRB1 (Figure 2), generic HLA-B (Figure 3), HLA-DRB1 and -DQB1 (Figure 4) and HLA-A, -B, -DRB1 and -DQB1 data (Figure 5). The latter were performed to confirm our results, as some of the populations included for comparison lacked high-resolution HLA-DRB1 data. This was carried out at the levels of NJ (Figures 2, 3, 4, 5), SGDs (Table 3), and correspondence analysis (Figure 6).
Neighbor-joining dendrogram showing relatedness between Southern Tunisians and other populations. Standard genetic distances (SGDs) between populations were calculated by using high-resolution HLA-DRB1 genotyping. Data from other populations were taken from references detailed in Table 1. Bootstrap values from 1.000 replicates are shown. Only individuals with defined DRB1 subtypes are considered. A full color version of this figure is available at the Journal of Human Genetics journal online.
Neighbor-joining dendrogram showing relatedness between Southern Tunisians and other populations. Standard genetic distances (SGDs) between populations were calculated by using generic HLA-B genotyping. Data from other populations were taken from references detailed in Table 1. Bootstrap values from 1.000 replicates are shown. A full color version of this figure is available at the Journal of Human Genetics journal online.
The frequencies of HLA alleles in Southern Tunisians were compared with those of other Arab-speaking, Mediterranean and sub-Saharan populations by high-resolution HLA-DRB1 (Figure 2), generic HLA-B (Figure 3), HLA-DRB1 and -DQB1 (Figure 4) and HLA-A, -B, -DRB1 and -DQB1 data (Figure 5). The latter were performed to confirm our results, as some of the populations included for comparison lacked high-resolution HLA-DRB1 data. This was carried out at the levels of NJ (Figures 2, 3, 4, 5), SGDs (Table 3), and correspondence analysis (Figure 6).
Neighbor-joining dendrogram showing relatedness between Southern Tunisians and other populations. Standard genetic distances (SGDs) between populations were calculated by using high-resolution HLA-DRB1 genotyping. Data from other populations were taken from references detailed in Table 1. Bootstrap values from 1.000 replicates are shown. Only individuals with defined DRB1 subtypes are considered. A full color version of this figure is available at the Journal of Human Genetics journal online.
Neighbor-joining dendrogram showing relatedness between Southern Tunisians and other populations. Standard genetic distances (SGDs) between populations were calculated by using generic HLA-B genotyping. Data from other populations were taken from references detailed in Table 1. Bootstrap values from 1.000 replicates are shown. A full color version of this figure is available at the Journal of Human Genetics journal online.